Pharm Ingredients
Ampelopsis Grossedentata Extract Dihydromyricetin
Ampelopsis Grossedentata Extract Dihydromyricetin Supplier
Dihydromyricetin is a flavonol isolated from the leaves and stems of Ampelopsis Grossedentata. It has antibacterial, antiviral, antitussive, anti-inflammatory, and antioxidant properties, and can reduce virus-induced lung inflammation and fibrosis. DHM is commonly used as an antioxidant, antibacterial agent, antiviral agent, and anticancer drug, and has also shown certain therapeutic potential for chronic diseases such as cancer, diabetes, and obesity.
kINTAI offers 30% Water-Soluble and 98% purity ampelopsin powder. For more information, please contact us！
kINTAI offers 30% Water-Soluble and 98% purity ampelopsin powder. For more information, please contact us！
Ampelopsis Grossedentata Extract Dihydromyricetin Natural Sources
DMY is widely found in various plants. Ampelopsis grossedentata is currently the plant with the highest known DMY content, and it is known as "vine tea" or "hairy rock plum" in China. DMY is found in the highest concentration in the tender stems and leaves of vine tea, exceeding 35% (w/w) of dry weight, making it the most important bioactive substance in vine tea. Therefore, vine tea is known as the "King of Flavonoids".
Hovenia dulcis Thunb is another natural source of DMY. Additionally, Dihydromyricetin is also abundant in a large evergreen conifer called Cedrus deodara G. Don, primarily found in its needles and pine branches. Therefore, Cedrus deodara needles are also used to make pine needle tea.
Extraction Source Advantages
1.Natural and safe raw material source
Vine tea itself is a natural plant with a long history of consumption, and its source is safe and reliable. Its leaves contain extremely high levels of natural dihydromyricetin, with no chemically synthesized residues.
2.High content of active ingredients
Ampelopsis Grossedentata is rich in dihydromyricetin, making it easy to obtain high-purity extracts. These highly active ingredients help enhance antioxidant and liver-protective effects.
3.Meet the demands of large-scale production
Vine tea can be planted and harvested on a large scale, meeting the growing market demand for dihydromyricetin raw materials and providing a sustainable advantage for its industrialization.
4.Component synergy
The core ingredient of vine tea extract is dihydromyricetin, which is clearly defined and easy to control and standardize. It may also retain other natural ingredients, which can synergistically enhance the effects of dihydromyricetin.
Ampelopsis Grossedentata Extract Dihydromyricetin Specification
Dihydromyricetin has the highest known flavonoid content among plants; therefore, our company primarily extracts dihydromyricetin from vine tea. If you require customized specifications and extraction sources, please contact us via email at: natural@kintaibio.com.
Ampelopsis Grossedentata Extract Dihydromyricetin Product Flow Chart
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Ampelopsis Grossedentata Vine Tea Extract Dihydromyricetin Benefits
1.Neuroprotection
DMY has multiple protective effects on the brain, improving learning and memory abilities and showing potential in combating Alzheimer's disease, Parkinson's disease, and depression. Its mechanisms include antioxidant, anti-apoptotic, anti-neuroinflammatory, and regulation of aging-related signaling pathways.
2.Anti-tumor Effects
Studies have shown that Dihydromyricetin has inhibitory activity against various cancer cells (such as liver cancer, lung cancer, osteosarcoma, ovarian cancer, etc.) and induces apoptosis. It works by interfering with the cell cycle, activating apoptosis signaling pathways, and inhibiting cancer cell invasion and metastasis.
3.Skin Protection and Whitening
Ampelopsis grossedentata extract powder can effectively inhibit tyrosinase activity and reduce melanin production, thus possessing whitening potential. Simultaneously, it can protect skin cells from UV damage and combat skin inflammation and melanoma by inhibiting pathways such as NF-κB.
4.Other benefits
It can relieve asthma symptoms by reducing airway inflammation; it can also enhance the vitality of mesenchymal stem cells and improve the success rate of cell transplantation therapy.
Dihydromyricetin Powder Drug Interactions
1.Drugs Affecting Liver Enzyme Metabolism
Studies have shown that DHM may affect the activity of liver metabolic enzymes, thereby altering the rate at which drugs are metabolized in the body. This may lead to reduced efficacy or increased toxicity of certain drugs, especially prescription drugs metabolized by liver enzymes.
2.With monoamine oxidase inhibitors (MAOIs)
Concomitant use of DHM and MAO inhibitors (such as isocarboxazid, phenelzine, selegiline, tranylcypromine, etc.) may lead to serious or even fatal drug interactions. DHM-related products should be used at least two weeks after discontinuing MAOIs.
3.With sedatives, hypnotics and central nervous system depressants
DHM may have some central nervous system modulatory effects, and its use in combination with the following drugs may increase the risk of drowsiness or sedation:
• Opioid analgesics (such as codeine, hydrocodone)
• Sedatives and anti-anxiety medications (such as alprazolam, lorazepam, zolpidem)
• Muscle relaxants (such as carisodoxetine, cyclobenzaline)
• Anthiamines (such as cetirizine, diphenhydramine)
• Alcohol or alcoholic beverages
4.With topical antihistamines
When used in combination with certain topical antihistamines (such as diphenhydramine cream, spray, ointment), it may enhance the efficacy or cause adverse reactions.
NOTE: Before using dihydromyricetin, please be sure to inform your healthcare provider of all the medications you are currently using. Do not adjust your medication on your own to avoid interactions.
When to Take Dihydromyricetin
1. Hangover Relief: Breaks down alcohol and reduces hangover symptoms.
Optimal Timing: 30-60 minutes before drinking, or during drinking (taken with alcohol).
Reason: Taking it in advance ensures that DHM reaches an effective concentration in the liver, so that it can immediately help accelerate the liver's metabolism of alcohol and harmful acetaldehyde when alcohol enters the system.
Replenishment Timing: After drinking/before bedtime.
Reason: Even after drinking, DHM still helps to clear residual acetaldehyde from the body, reducing hangover symptoms the next day.
2. Daily Health Maintenance (Liver Protection, Sleep Aid)
Optimal Time: Take with or after meals.
Reason: Food can help reduce potential irritation to the gastrointestinal tract and may improve bioavailability. If used to improve sleep, it is recommended to take it 30-60 minutes before bedtime.
Reference:
https://www.dhmguide.com/never-hungover/dhm-dosage-guide-2025
Ampelopsis Grossedentata Extract Dihydromyricetin Advantages
1. Pure and Traceable Raw Materials
Kintainutri® uses carefully selected premium Ampelopsis Grossedentata as its raw material, ensuring traceability and consistent quality. Natural extraction guarantees the product is free of chemical residues and meets international food and health product safety standards.
2.High-purity ampelopsin
Utilizing advanced extraction technology, DHM achieves a purity of up to 98%. This high purity ensures the bioavailability of the active ingredient and the stability of the product.
3.Excellent safety and stability
Kintainutri® undergoes rigorous quality testing and stability testing to ensure the product is free of heavy metals, pesticide residues, and other contaminants. Its low toxicity and high safety make it suitable for use in health supplements, functional beverages, and nutritional supplements.
If you have any specific needs, please feel free to contact us at any time. We will provide you with the most competitive ampelopsin dihydromyricetin powder price and services.
Shipping & Packaging
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● Packaging: Inside food grade bag, outer aluminum foil bag.25kg use double-layer plastic container/fiber drum.Or your choice.● OEM Service Available: Customized packaging available, click here to know more.● Shipping: DHL / FEDEX / EMS/ BY AIR / BY SEA● American Warehouse: KINTAI put over 100 natural plant extract ingredients in our US warehouse for fast delivery.● Payment: We accept payment by T/T, L/C, Paypal, and Wester Union.Please contact us and we will guide you with an easy and professional way for your order.
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