Healthcare Supplement
Berberine Chloride Hydrate Powder
Berberine Chloride Hydrate Powder
Kintainutri® is a leading supplier specializing in the research and production of plant extracts, dedicated to providing global customers with high-quality Berberine Chloride Hydrate powder.
We have ISO9001 quality management system and ISO22000 food safety management system certifications, ensuring full traceability and strict quality control from raw materials to finished products. We adopt ultrasonic-assisted extraction technology, which can more efficiently retain the biological activity of berberine compared to traditional methods, ensuring the purity of the final product to be above 97% without solvent residues.
All batches of products have passed heavy metal (lead, arsenic, mercury, cadmium) and pesticide residue as well as microbial limit tests, meeting the standards of the US FDA, EU EP, and Chinese Pharmacopoeia, and can provide complete COA and MSDS. Our berberine chloride Powder supports different packaging specifications (1kg/5kg/25kg), and can provide OEM/ODM services, including formula customization, capsule/ tablet filling, etc., to meet the diverse needs of customers, applicable to multiple fields such as medicine, health supplements, and cosmetics. We have our own planting base and modern production lines to ensure stable supply in large quantities, and also provide logistics tracking and technical after-sales support.
We have ISO9001 quality management system and ISO22000 food safety management system certifications, ensuring full traceability and strict quality control from raw materials to finished products. We adopt ultrasonic-assisted extraction technology, which can more efficiently retain the biological activity of berberine compared to traditional methods, ensuring the purity of the final product to be above 97% without solvent residues.
All batches of products have passed heavy metal (lead, arsenic, mercury, cadmium) and pesticide residue as well as microbial limit tests, meeting the standards of the US FDA, EU EP, and Chinese Pharmacopoeia, and can provide complete COA and MSDS. Our berberine chloride Powder supports different packaging specifications (1kg/5kg/25kg), and can provide OEM/ODM services, including formula customization, capsule/ tablet filling, etc., to meet the diverse needs of customers, applicable to multiple fields such as medicine, health supplements, and cosmetics. We have our own planting base and modern production lines to ensure stable supply in large quantities, and also provide logistics tracking and technical after-sales support.
what is Berberine Chloride Hydrate
Berberine Chloride Hydrate is a biogenic derivative extracted from natural plants and has extensive pharmacological activities and health application values.
Berberine is naturally present in various medicinal plants, such as Coptis chinensis, Phellodendron amurense, and Berberis vulgaris. We efficiently separate berberine from these plants using ultrasonic-assisted extraction technology and further purify it to produce berberine chloride ensuring high purity and biological activity.
The berberine chloride Powder provided by Kintainutri® is derived from Chinese wormwood. It is produced through strict purification and standardization to ensure high efficiency and safety, and is suitable for the global pharmaceutical, health care and cosmetic markets. If you need further information on technical parameters or application solutions, please feel free to contact us!
Partner with us for competitive wholesale pricing, flexible MOQs, and reliable global logistics. Contact us today for a quote!
Contact us Berberine Chloride Hydrate Production Process
Kintainutri® produces high-purity Berberine Chloride Hydrate powder through Ultrasonic-Assisted Extraction (UAE) technology, ensuring efficient extraction and optimal retention of active ingredients.
1. Raw material selection and pre-treatment
We select high-quality raw materials of Coptis plants and clean, dry, and crush them to achieve the most suitable particle size for extraction, thereby increasing the solubility rate of active ingredients.
2. Ultrasonic-assisted extraction
Under strict control of temperature, pH, and solvent concentration, we use high-frequency ultrasound (20-40kHz) to extract the raw materials. The cavitation effect produced by ultrasound can break the plant cell walls, significantly improving the solubility efficiency of berberine chloride, while reducing extraction time and the use of organic solvents.
3. Purification and crystallization
The extract is further purified through column chromatography with macroporous adsorption resin and recrystallization technology, removing impurities, and finally obtaining high-purity (≥97%) berberine chloride crystals.
4. Drying and standardization
The purified Berberine hlc is dried at low temperature by spray drying or vacuum freeze-drying to ensure product stability, and its content is tested according to HPLC standards to ensure that each batch of products meets the requirements of international pharmacopoeias (USP, EP, CP).
5. Strict quality inspection and packaging
All finished products undergo tests for heavy metals, pesticide residues, microbial limits, and solvent residues, and can be customized in 1kg/5kg/25kg packaging according to customer requirements to ensure safe transportation and storage.
The ultrasonic extraction process of Kintainutri® is not only highly efficient and environmentally friendly, but also can maximize the retention of the biological activity of Berberine hlc. This enables our Berberine Chloride Hydrate Powder to be at the forefront of the industry in terms of purity, safety and efficacy. If you need details of the process or customized production plans, please feel free to contact us at any time!
Berberine Chloride Hydrate Specification
| ITEMS | Standards |
| Assay | ≥98.3% |
| Appearance | Yellow powder |
| Water solution | Transpency, colorless, none suspendedmatetrs |
| Melting point | 202~206±0.5℃ |
| Optical rotation | ±174~186° |
| pH | 5.0~7.0 |
| Loss on drying | ≤0.5% |
| Lgnition residue | ≤0.5% |
| Heavy Metal | ≤20ppm |
| Arsenic (As) | ≤2ppm |
| Microbiology | |
| Total of bacteria | ≤1000cfu/g |
| Fungus | ≤100cfu/g |
| Salmonella | Negative |
| E.Coli | Negative |
| Conclusion: the test results conform to enterprise standards |
Berberine Chloride Hydrate Application
Kintainutri® high-purity Berberine Chloride Hydrate has become a core functional raw material in the global dietary supplement industry due to its outstanding metabolic regulation and health-promoting effects.
1. Blood sugar management and metabolic health
Berberine hlc can activate the AMPK signaling pathway, enhance cells' uptake and utilization of glucose, and inhibit liver gluconeogenesis. Clinical studies have shown that it can help maintain healthy blood sugar levels and is suitable for the auxiliary management of prediabetes and type 2 diabetes.
Berberine hlc can activate the AMPK signaling pathway, enhance cells' uptake and utilization of glucose, and inhibit liver gluconeogenesis. Clinical studies have shown that it can help maintain healthy blood sugar levels and is suitable for the auxiliary management of prediabetes and type 2 diabetes.
2. Cardiovascular health support
It regulates the expression of PCSK9 protein to reduce low-density lipoprotein cholesterol (LDL-C) and increase high-density lipoprotein (HDL), reducing the risk of atherosclerosis. Multiple studies have confirmed that long-term use can improve lipid abnormalities.
It regulates the expression of PCSK9 protein to reduce low-density lipoprotein cholesterol (LDL-C) and increase high-density lipoprotein (HDL), reducing the risk of atherosclerosis. Multiple studies have confirmed that long-term use can improve lipid abnormalities.
3. Gut microecological balance
Berberine hlchas broad-spectrum antibacterial properties, selectively inhibiting harmful bacteria (such as Escherichia coli, Helicobacter pylori), and promoting the proliferation of probiotics (such as Bifidobacterium), improving intestinal barrier function and digestive health.
Berberine hlchas broad-spectrum antibacterial properties, selectively inhibiting harmful bacteria (such as Escherichia coli, Helicobacter pylori), and promoting the proliferation of probiotics (such as Bifidobacterium), improving intestinal barrier function and digestive health.
4. Weight management assistance
By enhancing GLP-1 secretion and delaying fat synthesis, it can effectively inhibit appetite and promote the brownification of white fat, performing well in healthy weight loss formulation.
By enhancing GLP-1 secretion and delaying fat synthesis, it can effectively inhibit appetite and promote the brownification of white fat, performing well in healthy weight loss formulation.
5. Antioxidation and anti-aging
The isoquinoline group in its molecular structure can eliminate free radicals, reduce oxidative stress damage, and is often used in anti-aging supplements in combination with resveratrol, NMN, and other components.
The isoquinoline group in its molecular structure can eliminate free radicals, reduce oxidative stress damage, and is often used in anti-aging supplements in combination with resveratrol, NMN, and other components.
The Berberine Chloride Hydrate raw material of Kintainutri® boasts a pharmaceutical-grade purity of ≥98% and a standardized production process. It can be perfectly applied to: glucose management capsules/pills; cardiovascular and cerebrovascular health compound formula; intestinal conditioning powders; metabolic syndrome intervention products; anti-aging supplements. We provide complete technical document support to help customers develop more market-competitive supplement products. Now, consult to obtain samples and quotations!
Berberine Chloride Hydrate Dosage
| Application Form | Suggested Dosage Range | Notes |
|---|---|---|
| Dietary Supplements (Capsules/Tablets) | 300–500 mg, 2–3 times daily | Take with meals for optimal absorption |
| Powder for Functional Foods/Beverages | 50–200 mg per serving | Adjust based on formulation requirements |
Note: Dosage may vary depending on specific product formulations and regulatory guidelines in target markets.
Safety of Berberine Chloride Hydrate
Berberine Chloride Hydrate has good safety within the recommended dosage range (typically 900-1500mg per day), and no serious adverse reactions have been reported in long-term clinical use.
Some people may experience mild gastrointestinal discomfort (such as bloating and constipation), which is usually dose-related. It is recommended to take it with meals to reduce irritation.
Pregnant women, lactating women, and infants should avoid using it, as it may affect bilirubin metabolism; individuals with a tendency to low blood sugar should monitor their blood sugar levels.
Some people may experience mild gastrointestinal discomfort (such as bloating and constipation), which is usually dose-related. It is recommended to take it with meals to reduce irritation.
Pregnant women, lactating women, and infants should avoid using it, as it may affect bilirubin metabolism; individuals with a tendency to low blood sugar should monitor their blood sugar levels.
Why Choose Kintainutri® Berberine Chloride Hydrate?
1. Kintainutri® adopts ultrasonic-assisted extraction technology, which improves the extraction efficiency by more than 30% compared to traditional methods. This ensures high product purity and complete retention of active ingredients.
2. We offer pharmaceutical-grade purity (≥98%), and each batch of products is tested by HPLC and complies with international pharmacopoeia standards such as USP and EP.
3. Kintainutri® has ISO9001 and ISO22000 dual certifications. Every stage from raw materials to finished products undergoes strict quality control to ensure product safety and reliability.
4. We conduct strict tests for heavy metals, pesticide residues, and microorganisms. All test reports (COA) can be provided to meet global market compliance requirements.
5. Kintainutri® supports customized services, providing different specification packaging (1kg/5kg/25kg) and OEM/ODM solutions according to customer needs.
6. We have a stable supply chain and professional after-sales support to ensure timely delivery and provide technical consultation and formula optimization suggestions.
Choose Kintainutri®, and you will receive high-purity, high-quality, and cost-effective Berberine Chloride Hydrate raw materials, as well as professional, reliable, and flexible cooperation experience! If you need samples or detailed information, please feel free to contact us at any time.
Shipping & Packaging
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● Packaging: Inside food grade bag, outer aluminum foil bag.25kg use double-layer plastic container/fiber drum.Or your choice.● OEM Service Available: Customized packaging available, click here to know more.● Shipping: DHL / FEDEX / EMS/ BY AIR / BY SEA● American Warehouse: KINTAI put over 100 natural plant extract ingredients in our US warehouse for fast delivery.● Payment: We accept payment by T/T, L/C, Paypal, and Wester Union.Please contact us and we will guide you with an easy and professional way for your order.
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