Pharm Ingredients
Fisetin Powder Manufacturers
Fisetin Powder, a natural flavonoid compound and one of Kintainutri®'s core plant extracts, is primarily derived from the natural plant of Cotinus coggygria, a member of the Anacardiaceae family, and is produced through advanced extraction and purification processes. This product is a bright yellow fine powder, odorless, and well-soluble. Standard supply specifications contain 10%-98% fisetin purity (HPLC assay), and various purity grades can be customized upon request. It exhibits excellent antioxidant properties, helping to scavenge free radicals.
| Product Name | Specification | Test Method |
|---|---|---|
| Fisetin Powder | 10%, 20%, 50%, 70%, 85% | HPLC |
| 98% | HPLC Area Normalization / HPLC External Standard |
As a popular anti-aging ingredient, it excels in supporting healthy aging and maintaining cell vitality. It has a wide range of applications, including dietary supplements (such as capsules and tablets), functional foods, and cosmetic ingredients. As a professional plant extract powder supplier with years of experience in the industry, Kintainutri® consistently adheres to product standards of "naturalness, high purity, and stability." From raw material selection to production quality control, strict GMP regulations are adhered to ensure that every batch of Fisetin Powder meets international quality standards, providing reliable raw material support to global customers.
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Fisetin Powder COA
How To Make Fisetin Powder?
Fisetin Powder Benefits
Fisetin testosterone
Research indicates that fisetin powder significantly ameliorates testicular toxicity in male rats through dual central and peripheral mechanisms. Key benefits include increased testosterone levels, elevated sperm counts, and reduced sperm deformity rates. At the central level, fisetin restores glutamate-induced dysfunction of the hypothalamic-pituitary-gonadal (HPG) axis, thereby normalizing the secretion of gonadotropin-releasing hormone, follicle-stimulating hormone, luteinizing hormone, and testosterone.
At the peripheral level, it activates the SIRT1/pAMPK signaling pathway in testicular tissue while reducing oxidative stress markers, including hydrogen peroxide, nitric oxide, and NOX4 gene expression, and increasing levels of endogenous reduced glutathione. These effects help preserve spermatogenic cell structure and improve sperm quality. These findings provide experimental evidence supporting the potential use of fisetin as a functional ingredient for male reproductive health, making it particularly suitable for developing antioxidant and hormone-supporting health products.
Fisetin and cancer
The core value of fisetin in the adjuvant treatment of cancer lies in its ability to inhibit tumor cell migration and invasion. Fisetin significantly downregulates the expression of uPA (urokinase-type plasminogen activator) by simultaneously inhibiting the signaling molecules NF-κB (p65) and p-p38, thereby blocking their nuclear translocation and subsequent activation of uPA promoter transcription, which ultimately suppresses tumor cell migration and invasion.
These findings provide a clear molecular basis for using fisetin powder as a functional ingredient to combat tumor metastasis; furthermore, given its potential to alleviate chemotherapy-induced tissue damage. Kintainutri®’s fisetin powder is suitable for development as a functional ingredient for the adjunctive treatment of tumors, particularly for the formulation of combination products designed for cancer supportive care.
What Is Fisetin Powder Used For？
Fisetin supplement
In the dietary supplement industry, fisetin supplements are primarily positioned as natural anti-aging and health-maintenance products. To address the challenge of low oral absorption, mainstream market solutions have shifted from conventional raw materials to finished formulations utilizing advanced delivery technologies, such as liposomal encapsulation and nano-emulsification, to significantly enhance in vivo bioavailability.
These products are mainly targeted at middle-aged and older adults seeking healthy aging solutions. By activating longevity-related proteins such as SIRT1 and promoting the clearance of senescent cells, fisetin supplements support cognitive function, maintain immune homeostasis, and improve metabolic health. They are particularly suitable for incorporation into anti-aging capsules, oral liquids, and functional solid beverages, meeting the differentiated demands of the premium anti-aging market.
Functional foods
Fisetin can be added to foods such as breakfast cereals, protein powders, solid beverages, and compressed candies. For example, adding 0.5%-1% fisetin powder to functional cereals specifically formulated for middle-aged and elderly individuals does not affect the original taste of the food while providing the product with antioxidant and light health benefits. Its properties align with current healthy eating trends.
Cosmetics
With its excellent antioxidant capacity, it can be added as an active ingredient in skincare products such as anti-wrinkle creams, serums, and eye creams. Typical addition levels are 0.1%-0.5%. It helps scavenge free radicals and slow collagen loss. When combined with ingredients like hyaluronic acid and vitamin C, it enhances skin moisturizing and anti-aging effects. Its high purity and impurity-free nature reduce the risk of skin allergies.
Research and pharmaceutical intermediates:
High-purity (≥98%) Fisetin can be used as an experimental raw material by research institutions and pharmaceutical companies for applications such as aging mechanism research and drug development. Kintainutri® offers customized purity (up to 99.5%) and small-batch packaging to meet the precise needs of research experiments.
Fisetin Powder Dosage
Application Field |
Recommended Addition Level |
Typical End-Product Form |
Dietary Supplements |
100 - 500 mg per serving |
Capsules, Tablets, Powder Blends |
Functional Foods |
0.5% - 1% of total formula |
Breakfast Cereals, Protein Powders, Solid Drinks |
Note: The above dosages are for reference only. Kintainutri® recommends adjusting based on specific product formulas, regional regulatory requirements, and target efficacy.
Where To Buy Fisetin Powder?
As a professional supplier of plant extracts, Kintainutri®'s Fisetin powder offers reliable quality and service to downstream manufacturers. Key reasons for choosing Kintainutri® are:
Strict quality control and stable purity: Raw materials are sourced from compliant plantations with full traceability. HPLC is used throughout the production process to ensure Fisetin's purity remains stable at ≥98%. Heavy metal (lead, mercury, etc.) and microbiological indicators are significantly below international standards. Each batch of product is accompanied by a complete Certificate of Analysis (COA), ensuring reliable use in production without the need for additional testing.
Flexible customization to meet diverse needs: Powder fineness (80-200 mesh) and packaging specifications (from 1kg bags to 25kg drums) can be customized based on the characteristics of the customer's end product. Small batches as small as 100g are also available for trial use, helping customers reduce R&D and pilot production costs and rapidly accelerate product launch. Efficient Response, Full-Life Service: Dedicated account managers respond to inquiries and orders within 24 hours. We provide MSDS, FDA filings, and other certification documents to assist customers with market regulation and compliance audits. We partner with renowned international freight forwarders for logistics, ensuring timely and safe product delivery.
Cost Advantages, Outstanding Value: Through large-scale raw material procurement and optimized extraction processes (ethanol recovery rate ≥ 95%), we reduce production costs while ensuring quality. We provide customers with competitive quotes and help them increase their end-product profit margins.
Strict quality control and stable purity: Raw materials are sourced from compliant plantations with full traceability. HPLC is used throughout the production process to ensure Fisetin's purity remains stable at ≥98%. Heavy metal (lead, mercury, etc.) and microbiological indicators are significantly below international standards. Each batch of product is accompanied by a complete Certificate of Analysis (COA), ensuring reliable use in production without the need for additional testing.
Flexible customization to meet diverse needs: Powder fineness (80-200 mesh) and packaging specifications (from 1kg bags to 25kg drums) can be customized based on the characteristics of the customer's end product. Small batches as small as 100g are also available for trial use, helping customers reduce R&D and pilot production costs and rapidly accelerate product launch. Efficient Response, Full-Life Service: Dedicated account managers respond to inquiries and orders within 24 hours. We provide MSDS, FDA filings, and other certification documents to assist customers with market regulation and compliance audits. We partner with renowned international freight forwarders for logistics, ensuring timely and safe product delivery.
Cost Advantages, Outstanding Value: Through large-scale raw material procurement and optimized extraction processes (ethanol recovery rate ≥ 95%), we reduce production costs while ensuring quality. We provide customers with competitive quotes and help them increase their end-product profit margins.
Shipping & Packaging
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● Packaging: Inside food grade bag, outer aluminum foil bag.25kg use double-layer plastic container/fiber drum.Or your choice.● OEM Service Available: Customized packaging available, click here to know more.● Shipping: DHL / FEDEX / EMS/ BY AIR / BY SEA● American Warehouse: Kintainutri® put over 100 natural plant extract ingredients in our US warehouse for fast delivery.● Payment: We accept payment by T/T, L/C, Paypal, and Wester Union.Please contact us and we will guide you with an easy and professional way for your order.
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