Healthcare Supplement
Urolithin A Powder
Urolithin A Manufacturer & Supplier—Kintainutri® Factory
Kintainutri, a leading Urolithin A supplier in China, boasts over ten years of extraction experience and technology. We utilize a bio-fermentation process to produce Urolithin A powder with a purity of up to 98% and stable composition, certified by HPLC. Specific information on Urolithin A is as follows:
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Urolithin A is a metabolite produced by intestinal bacteria from ellagitannins (polyphenolic compounds derived from various plant-based foods). Structurally, it is identical to compounds endogenously formed after humans consume ellagitannins and ellagic acid found in various fruits and nuts. It is a natural metabolite of ellagitannins, a class of compounds found in pomegranates and some other fruits and nuts. Studies have shown that it possesses anti-inflammatory, anti-aging, antioxidant, and mitophagy-inducing effects, and can cross the blood-brain barrier.
Urolithin A Powder COA
How to Get Urolithin A powder?
Is Urolithin A Powder Legit?
In the United States, Urolithin A is an FDA-approved ingredient that can be used in foods (e.g., protein shakes, meal replacement drinks, instant oatmeal) and dietary supplements under its GRAS status.
Reference: https://www.fda.gov/food/gras-notice-inventory/recently-published-gras-notices-and-fda-letters
Urolithin A powder COA Health Benefits
Urolithin A Benefits For Skin
Studies show that urolithiasis A can effectively combat internal skin aging, not only significantly reducing wrinkles and improving skin hydration, but also without affecting the skin barrier function; at the molecular level, it can promote collagen synthesis and inhibit its degradation, while enhancing mitochondrial autophagy. For photodamage, urolithiasis A can significantly reduce erythema and inflammation caused by UVB.
Furthermore, this ingredient is safe for topical use, with no serious adverse reactions, no irritation or sensitization, and good tolerability. It supports skin health and long-term maintenance through the regulation of collagen and mitochondrial pathways, allowing you to confidently use it in various skincare products.
Urolithin A For Alzheimer's
As a gut microbial metabolite of ellagic acid, urolithin A has shown clear potential in the intervention of Alzheimer's disease. Studies have shown that it can effectively improve cognitive function in AD model animals. The core mechanism is to restore lysosomal function and induce mitophagy, clearing disease-causing β-amyloid protein and phosphorylated tau protein deposits, and enhancing synaptic plasticity. In addition, UA has good blood-brain barrier penetration, and its clinical safety has been preliminarily verified, laying a solid foundation for its development as an intervention product for neurodegenerative diseases.
Reference: https://www.mdpi.com/2076-3921/13/9/1027；
Urolithin A and Cancer
Urolithiasis A has a broad-spectrum anti-tumor effect in cancer treatment, and can target various cancer types such as breast, colorectal, liver, glioblastoma, pancreas, prostate, bladder, melanoma, non-small cell lung cancer, and cholangiocarcinoma.
It primarily enhances cellular metabolic metabolism by regulating autophagy (especially mitophagy that clears damaged mitochondria), while also directly inducing apoptosis in cancer cells, arresting the cell cycle, and inhibiting tumor progression and metastasis pathways.
Furthermore, it optimizes the tumor microenvironment, blocks angiogenesis, and reduces inflammatory responses. More importantly, it significantly enhances the efficacy of chemotherapy, radiotherapy, and immunotherapy, providing core competitiveness for the development of novel anticancer drugs and functional dietary supplements, making it an excellent choice for your investment in the anti-tumor health industry.
Urolithin A For Weight Loss
Based on animal experimental evidence, urolithin A has shown the potential to combat obesity and improve metabolism by regulating the gut microbiota. In a high-fat diet-induced obese rat model, it effectively slowed weight gain and improved blood lipids (such as increasing high-density lipoprotein and reducing total cholesterol and triglycerides). Its core mechanism lies in reshaping the disordered gut microbiota, including reducing the ratio of Firmicutes/Bacteroidetes associated with obesity, reducing pro-inflammatory bacteria (such as Desulfovibrioceae), and increasing beneficial bacteria that can produce short-chain fatty acids (such as Parabacterium), thereby improving host metabolism.
Furthermore, urolithin A also showed effects in preventing weight gain, improving insulin resistance, hyperglycemia, and fatty liver in a genetically obese mouse model, with no significant side effects observed at experimental doses. These findings provide a mechanistic basis for its potential as an anti-obesity agent, but its human efficacy still requires further validation through clinical trials.
What is Urolithin A Used For?
Urolithin A, as a natural compound with a variety of biological activities, shows broad market application prospects. In the health supplement industry, it can be used not only to develop anti-aging products, but also shows potential in promoting cardiovascular health, enhancing muscle performance and exercise recovery. With the continuous deepening of relevant research and the ongoing improvement of consumers' understanding of natural health ingredients, urolithiasis A is expected to play an increasingly important role in the future health supplement market.
Urolithin A Safety
Urolithin A is a natural compound with good safety and tolerability. Current studies show that it has not caused toxicity or specific adverse reactions in vivo. In 2018, the U.S. FDA set the safe dosage range for it in food at 250 to 1,000 milligrams per serving.
The ingredient's positive effects on the gut and skeletal muscle have been stable in older adults, making it suitable for long-term use to support healthy aging. No serious side effects have been reported in studies, indicating a reliable safety profile in improving age-related muscle function decline.
Reference: https://journals.lww.com/nrronline/fulltext/2025/01000/pyrroloquinoline_quinone__a_potential.5.aspx.
For more information about Urolithin A powder, please feel free to contact us at any time.
Shipping & Packaging
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● Packaging: Inside food grade bag, outer aluminum foil bag.25kg use double-layer plastic container/fiber drum.Or your choice.● OEM Service Available: Customized packaging available, click here to know more.● Shipping: DHL / FEDEX / EMS/ BY AIR / BY SEA● American Warehouse: KINTAI put over 100 natural plant extract ingredients in our US warehouse for fast delivery.● Payment: We accept payment by T/T, L/C, Paypal, and Wester Union.Please contact us and we will guide you with an easy and professional way for your order.
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Yes, quillaia extract can indeed cause allergies, but this primarily occurs in occupational groups frequently exposed to its dust, potentially leading to symptoms such as asthma and rhinitis. This is an immediate allergic reaction mediated by IgE. However, the risk of triggering an allergic reaction is lower when it is used as a compliant food or cosmetic additive. Therefore, those with occupational exposure or highly sensitive individuals should exercise caution, while ordinary consumers generally do not need to worry excessively in daily use. -
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