Pharm Ingredients
Cordyceps Sinensis Extract Powder
What is Cordyceps Sinensis Extract
Cordyceps sinensis extract powder is a powdered product made from the fruiting bodies of Cordyceps militaris. Through advanced extraction processes, the active ingredients in Cordyceps militaris, such as cordycepin, adenosine, and polysaccharides, are effectively preserved.
kINTAI mainly provides 10%-50% Polysaccharides, 0.3%-1% Adenosine, 0.3%-8% Cordycepin. Contact us now to get free samples and detailed technical guidance!
These components endow cordyceps militaris extract with various benefits, including antioxidant, anti-glycation, skin barrier repair, and anti-inflammatory and soothing effects, this has created high demand for it in the skincare industry.
Meanwhile, cordyceps mushroom extract also has certain effects in regulating immunity, improving respiratory function, and regulating blood sugar levels, and is widely used in the fields of medicine, health products, and food.
kINTAI mainly provides 10%-50% Polysaccharides, 0.3%-1% Adenosine, 0.3%-8% Cordycepin. Contact us now to get free samples and detailed technical guidance!
Cordyceps Sinensis Extract Powder Extraction Source
Cordyceps militaris (L.ex Fr.) Link. is a fungus belonging to the family Clavicipitaceae and the genus Cordyceps. Also known as North Cordyceps, it is a fungus used for both food and medicine. It is rich in cordycepic acid, cordycepin, ergosterol, and other compounds. Cultivated Cordyceps militaris also contains abundant vitamins and minerals, making it highly valuable for consumption.
The main bioactive components of Cordyceps militaris
·Nucleoside compounds:
Cordyceps militaris contains various nucleoside compounds, including cordycepin (3'-deoxyadenosine), adenosine, adenine, uridine, and guanine derivatives. Among these, cordycepin is a hot research topic, possessing excellent anti-inflammatory, immune-enhancing, and anti-cancer effects.
• Cordyceps polysaccharides:
The polysaccharide content in Cordyceps militaris is 4%–10%. It is usually a highly branched mannan or galactomannan composed of reducing sugars such as glucose, galactose, and mannose.
• Cordycepic acid:
Cordycepic acid, also known as D-mannitol, has the effects of inhibiting bacteria, anti-oxidation, and promoting metabolism. It can be used to prevent and treat cardiovascular and cerebrovascular diseases and renal failure.
• Protein, amino acids, and sterols:
Rich in protein, including all seven essential amino acids; sterols (cordycepic acid) have diuretic, detoxifying, and metabolism-boosting functions.
• Minerals and Vitamins:
Cordyceps mycelium contains more than 20 kinds of minerals, among which the content of Ca and K is higher than that of Cordyceps sinensis. It is also rich in a variety of vitamins, and except for niacin, the content of most vitamins is much higher than that of Cordyceps sinensis.
Cordyceps Sinensis Extract Powder COA
Cordyceps Sinensis Extract Benefits
1.Protect the liver
Regarding liver protection, it can lower serum transaminase levels, inhibit hepatic stellate cell activation to alleviate liver fibrosis, and promote hepatocyte repair and regeneration. In terms of kidney and lung protection, it contains various trace elements that nourish the lungs and kidneys, and cordycepic acid has a diuretic effect, making it clinically useful in the treatment of renal failure. Simultaneously, it can protect the lungs from free radical damage and delay lung function decline.
2.Relieve Fatigue
It can enhance mitochondrial function, increase ATP synthesis to replenish the body's energy, and improve the oxygen-carrying capacity of hemoglobin, thus enhancing oxygen delivery efficiency. By regulating immune function, improving endocrine and energy metabolism, it can accelerate the body's recovery process. Appropriate use can effectively relieve fatigue, improve exercise endurance, and enhance overall physical function.
3.Regulate Blood Sugar
This cordyceps mushroom extract can enhance cellular sensitivity to insulin, promote glucose uptake and utilization, thereby lowering blood sugar levels. It can also stimulate insulin secretion, helping to regulate blood sugar; and it can maintain stable blood sugar levels by affecting glucose metabolism enzymes. Animal and clinical studies have shown its good potential for adjunctive blood sugar lowering.
4.Maintain cardiovascular and respiratory health
Cordyceps mycelium extract contains components such as adenosine, which can enhance myocardial contractility, improve cardiac function, dilate blood vessels to promote blood circulation, and help lower blood pressure and reduce the burden on the heart. Its anti-inflammatory effects can reduce vascular inflammation and lower the risk of cardiovascular disease. For the respiratory system, it can increase lung capacity and oxygen utilization, and alleviate symptoms of chronic respiratory diseases such as COPD and asthma.
Mechanism of Cordyceps Sinensis extract in lowering uric acid
1.Key enzyme activity inhibiting uric acid production
Cordyceps militaris extract reduces uric acid production by inhibiting the activity of xanthine oxidase (XOD). XOD is a key enzyme in uric acid synthesis, catalyzing the conversion of hypoxanthine and xanthine into uric acid.
Experiments have shown that Cordyceps militaris extract can significantly reduce the activity of XOD in the liver of rats with hyperuricemia, thereby lowering serum uric acid levels. Furthermore, its active ingredient, cordycepin, has also been shown to inhibit XOD, further reducing uric acid production.
2.Regulation of renal uric acid transporter expression
The kidneys are the main organs for uric acid excretion. Cordyceps Sinensis extract promotes uric acid excretion by regulating the expression of uric acid transport proteins.
- Downregulate reabsorption proteins such as urate anion transporter 1 (URAT1) and glucose transporter 9 (GLUT9) to reduce uric acid reabsorption.
- Upregulate excretory proteins such as organic anion transporter 1 (OAT1) and adenosine triphosphate binding cassette transporter G2 (ABCG2), enhancing uric acid excretion.
This dual regulatory mechanism significantly reduced serum uric acid levels and alleviated kidney damage in animal experiments.
3.Improve gut microbiota balance
Gut microbiota dysbiosis is closely related to hyperuricemia. Cordyceps mushroom extract can regulate gut microbiota composition.
- Increases the abundance of probiotics in Firmicutes and Bacteroidetes, which are significantly positively correlated with uric acid metabolism indicators such as UA and CRE.
- Improves intestinal inflammation and reduces the reabsorption of uric acid in the intestine through metabolites (such as short-chain fatty acids).
The study also found that Cordyceps militaris extract can restore the balance of gut microbiota in an LPS-induced intestinal inflammation model, further alleviating systemic inflammatory responses.
4.Antioxidant and anti-inflammatory effects
Hyperuricemia is often accompanied by oxidative stress and inflammatory responses. Cordyceps militaris extract exerts its effects through the following pathways:
- Scavenging free radicals: The polysaccharide components significantly enhance glutathione (GSH) and total antioxidant capacity (T-AOC), reduce malondialdehyde (MDA) content, and alleviate oxidative damage.
- Inhibit inflammatory pathways: Downregulate the expression of NLRP3 inflammasome and pro-inflammatory factors (such as IL-1β, IL-6, TNF-α) to block the inflammatory cascade.
For example, in a piglet intestinal inflammation model, Cordyceps militaris extract alleviated oxidative stress and inflammation by regulating complement and coagulation cascades.
Cordyceps Sinensis Extract in Skin Care
Cordyceps militaris, also known as North Cordyceps sinensis, is a famous Chinese fungus used for both medicinal and edible purposes. It is rich in various active ingredients such as cordycepin, cordycepic acid, and cordyceps polysaccharides. It not only has oral health benefits such as improving immunity and prolonging life, but also has skin-beautifying effects such as anti-oxidation, firming, brightening, and anti-aging. Cordyceps extract is also very popular in the skin care market.
1.Antioxidant and anti-glycation
Cordyceps militaris extract is rich in active ingredients such as cordycepin and polysaccharides, which can effectively eliminate free radicals, reduce the damage of oxidative stress to the skin, and delay aging. Meanwhile, its anti-glycation effect can inhibit the formation of advanced glycation end products (AGEs) and improve skin dullness and sagging caused by high-sugar diets or ultraviolet rays.
2.Anti-inflammatory and soothing
Ingredients such as adenosine can regulate skin immunity, inhibit the expression of inflammatory factors, and relieve problems such as redness and itching in sensitive skin. It also has potential therapeutic effects on contact dermatitis and allergic inflammation.
3.Repair and Moisturize
Polysaccharide ingredients can enhance the skin barrier function, promote the repair of the stratum corneum, improve the skin's moisturizing ability, and make the skin softer and smoother.
4.Anti-photoaging and firming
It can block the expression of matrix metalloproteinases (MMPs) induced by ultraviolet radiation, reduce collagen loss, improve skin elasticity, and prevent wrinkles and sagging caused by photoaging.
5.Promote autophagy and regeneration
It can activate autophagy, help clear damaged cellular components, promote collagen synthesis, and enhance the skin's repair ability and radiance.
Related skincare product characteristics
Natural and safe: Plant-derived fermentation, gentle and low-irritant, suitable for sensitive skin.
Multi-functional: Simultaneously addresses two core aging issues: oxidation and glycation.
Rare and valuable: Compared to ordinary plant extracts, cordyceps-based ingredients have greater potential for premiumization.
Why go to Kintainutri® to buy Cordyceps Sinensis Extract Powder?
1.Diverse categories
Xi'an Kintai offers a variety of Cordyceps sinensis extract powder products in various specifications and purities to fully meet the needs of different usage scenarios. Leveraging a mature production system, we have ample stock, allowing for quick procurement without long waiting times. This combination of diverse product categories and ample stock makes the procurement process more efficient and effectively reduces inventory turnover pressure.
2.Comprehensive qualifications
We possess comprehensive industry qualifications and certifications, such as GMP, ISO9001, HACCP, KOSHER, and HALAL, ensuring that our production processes are standardized and comply with international standards. Furthermore, we have established a robust quality traceability system, with detailed records kept for every step from raw material warehousing to finished product delivery, allowing for real-time traceability and verification. These comprehensive qualifications and rigorous traceability system provide a strong defense for product quality, giving you greater peace of mind when purchasing.
3.Factory Direct Pricing
As the source of production, we eliminate middlemen, offering you highly competitive factory prices. This directly reduces your raw material procurement costs and enhances the market competitiveness of your finished products. Choosing us means choosing a stable supply with high cost-effectiveness.
4.Timely Delivery
We have large raw material and finished product warehouses with ample stock of regular products, enabling us to quickly respond to your order needs. Regardless of the size of your order, we promise efficient delivery, ensuring your production schedule is maintained.
If you have any specific needs about Cordyceps Sinensis Mycelium Extract Powder, please feel free to contact us at any time. We will provide you with the most competitive Cordyceps Militaris extract price and services.
Shipping & Packaging
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● Packaging: Inside food grade bag, outer aluminum foil bag.25kg use double-layer plastic container/fiber drum.Or your choice.● OEM Service Available: Customized packaging available, click here to know more.● Shipping: DHL / FEDEX / EMS/ BY AIR / BY SEA● American Warehouse: KINTAI put over 100 natural plant extract ingredients in our US warehouse for fast delivery.● Payment: We accept payment by T/T, L/C, Paypal, and Wester Union.Please contact us and we will guide you with an easy and professional way for your order.
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