Healthcare Supplement
Palmitoylethanolamide Powder
Kintainutri® Factory Wholesale Price Palmitoylethanolamide PEA Powder
Kintainutri® specializes in the production and supply of high-purity palmitoylethanolamide PEA powder. We employ chemical synthesis processes and rigorous HPLC testing to ensure palmidrol purity exceeds 99%, offering customers a variety of specifications from standard to ultrafine powders.
Specifications of PEA are listed below.
Hydroxyethylpalmitamide is a fatty acid amide naturally produced by the human body and many other organisms. It has powerful anti-inflammatory, analgesic, and neuroprotective effects. It can regulate peripheral nerve pain signals, inhibit pain transmission, reduce inflammation, effectively relieve chronic pain, improve pain-related sleep disorders, and enhance daily activity abilities.
Currently, the application of PEA has expanded from the field of pain management to areas such as dietary supplements, functional foods, and local soothing care products.
Contact us Palmitoylethanolamide Powder Specification
| Item | Specifications | Results |
|---|---|---|
| Appearance | White powder | Conforms |
| Assay | ≥99.0% | 99.36% |
| Moisture | 2.0% Max | 0.89% |
| Residue on Ignition | 1.0 Max | Conforms |
| Identification | Positive | Conforms |
| Heavy Metals | ≤10 ppm | Conforms |
| Arsenic | ≤1.0 ppm | Conforms |
| Sulfate | ≤0.04 ppm | Conforms |
| Iron | ≤10 ppm | Conforms |
| Chloride | ≤0.02 ppm | Conforms |
| Solvent Residual | Meeting USP Standard | Conforms |
| Microbiological Tests | ||
| Total plate count(cfu/g) | ≤10000 cfu/g | ＜10 cfu/g |
| Total Yeast & mold | ≤300 cfu/g | ＜10 cfu/g |
| E.Coliforms | ≤10 cfu/g | Conforms |
| S.aureus | Negative/10g | Conforms |
| Salmonella | Negative/25g | Conforms |
| Pseudomonas aeruginosa | Negative/25g | Conforms |
| Conclusion | Confirm to Specification and Standards. | |
Palmitoylethanolamide Powder Production Process
Regulatory Status of Palmitoylethanolamide Powder
Palmitoylethanolamide has not yet been approved by the U.S. FDA for formal marketing as a drug. However, its ultra-micro powdered formulation (um-PEA) has been authorized by the FDA to conduct clinical trials, aiming to evaluate the efficacy and safety of ultra-micro palmitoyl ethanolamide (um-PEA) as an adjunctive therapy in hospitalized COVID-19 patients, demonstrating its clinical research value as a potential adjunctive treatment option.
Palmitoylethanolamide Powder Benefits
Palmitoylethanolamide For Anxiety
Studies have confirmed that Palmitoyl ethanolamide possesses anti-anxiety and neuroprotective effects in obese mouse models. These effects are primarily achieved by reducing systemic and cerebral inflammation, protecting the integrity of the blood-brain barrier, regulating the neurochemical homeostasis of anxiety-related brain regions (such as the amygdala and hypothalamus), and inhibiting the overactive stress response system (HPA axis). Therefore, it could be used as a potential drug or functional ingredient for developing treatments for obesity-related anxiety.
Image & Reference: https://www.sciencedirect.com/science/article/pii/S088915912200037X#f0040.
Palmitoylethanolamide Powder For Weight Loss
N-Palmitoylethanolamine promotes the transformation of white adipocytes into beige adipocytes with thermogenic function by activating PPAR-α, thereby enhancing energy expenditure and reducing fat accumulation. Simultaneously, it improves leptin sensitivity, regulates the expression of appetite-related neuropeptides in the hypothalamus, suppresses appetite, and promotes energy expenditure. Furthermore, PEA reduces systemic and neuroinflammatory symptoms, improves gut microbiota and metabolic function, thereby synergistically improving metabolic health and reducing fat accumulation, with potential benefits, especially for menopausal or obesity-related weight gain.
Reference: https://www.mdpi.com/2072-6643/16/24/4313; https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2023.1143004/full.
Palmitoylethanolamide Powder For Pain Relief
As an endogenous lipid mediator, palmitic acid monoethanolamide exerts its anti-inflammatory, analgesic, and neuroprotective effects by activating PPAR-α receptors to inhibit the NF-κB pathway, reducing the release of pro-inflammatory cytokines, and synergistically regulating neurotransmission with the endocannabinoid system. Clinical studies have shown that PEA has good safety and tolerability in various types of pain, including chronic pain, neuropathic pain, fibromyalgia, and low back pain. It is especially suitable for use in combination with traditional analgesics to enhance efficacy and reduce dependence and side effects.
Image & Reference: https://www.dovepress.com/palmitoylethanolamide-in-the-treatment-of-pain-and-its-clinical-applic-peer-reviewed-fulltext-article-DDDT#f0003.
Palmitoylethanolamide Powder Uses
Palmitoylethanolamide Supplement
Palmitoylethanolamide supplements are mainly in the form of dietary supplements, covering single-dose formulations such as ultra-micro powder/micro powder and cold water dispersible type. They can also be compounded with ingredients such as luteolin and alpha-lipoic acid to form compound formulations. Oral forms include various types such as capsules, tablets, and sublingual microparticles.
Its core efficacy lies in anti-inflammatory, analgesic, and neuroprotective effects. It can not only help improve various pain symptoms such as neuropathic pain, migraines, and arthritis, but also help alleviate neuropsychiatric symptoms such as autism and depression. It can also help manage symptoms of visceral diseases such as glaucoma and irritable bowel syndrome. At the same time, it has good safety and tolerability, making it a supplement ingredient that you can trust.
Its core efficacy lies in anti-inflammatory, analgesic, and neuroprotective effects. It can not only help improve various pain symptoms such as neuropathic pain, migraines, and arthritis, but also help alleviate neuropsychiatric symptoms such as autism and depression. It can also help manage symptoms of visceral diseases such as glaucoma and irritable bowel syndrome. At the same time, it has good safety and tolerability, making it a supplement ingredient that you can trust.
Is Palmitoylethanolamide Safe?
Studies have shown that palmitoylethanolamide powder has good safety and tolerability. Relevant clinical trials and research data show that, whether used alone or in combination with ingredients such as superoxide dismutase, alpha-lipoic acid, and B vitamins, no significant side effects were observed even with long-term (e.g., 6 months) daily use.
PEA in micronized and ultramicronized formulations pose no risk of toxicity or genotoxicity and has shown good tolerability in special populations such as the elderly. Compared with traditional analgesics, PEA does not have serious adverse reactions such as addiction or gastrointestinal bleeding, has a wide safe dosage range, and has no obvious drug interactions. It is suitable for people who need long-term pain relief, and no serious safety risks have been found due to the use of PEA.
Reference: https://www.mdpi.com/2072-6643/16/18/3045.
Where to Buy Palmitoylethanolamide Powder?
Leveraging our Kintainutri® professional factory R&D capabilities, we provide high-purity palmitic acid monoethanolamide powder, offering reliable raw material solutions for neuroprotection, inflammation control, and pain management. Whether you are dedicated to neuroscience research or developing anti-inflammatory and analgesic supplements, our palmitoylethanolamide powder can meet your needs.
*Kintainutri® Promise All Products: Non-Irradiated / Non-ETO/ Treat by Heat Only / Non-GMO
Shipping & Packaging
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● Packaging: Inside food grade bag, outer aluminum foil bag.25kg use double-layer plastic container/fiber drum.Or your choice.● OEM Service Available: Customized packaging available, click here to know more.● Shipping: DHL / FEDEX / EMS/ BY AIR / BY SEA● American Warehouse: KINTAI put over 100 natural plant extract ingredients in our US warehouse for fast delivery.● Payment: We accept payment by T/T, L/C, Paypal, and Wester Union.Please contact us and we will guide you with an easy and professional way for your order.
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