Pharm Ingredients
Rabdosia Rubescens Extract Oridonin
Rabdosia Rubescens Extract Oridonin Supplier
Kintainutri® is a professional plant extract manufacturer in China. We use safe ethanol solvent to extract 0.5%, 1%, 5%, and 98% purity of Oridonin and Ponicidin from rabdosia rubescens. Specific specifications are as follows:
Isodon rubescens is rich in various components such as terpenes, alkaloids, volatile oils, polysaccharides, and amino acids, among which oridonin A and oridonin B are its main active ingredients.
These components have significant anti-tumor and antibacterial effects, especially in treating early-stage esophageal cancer, and also have a significant inhibitory effect on common upper respiratory tract pathogens such as Staphylococcus aureus and Streptococcus pyogenes.
Therefore, rabdosia rubescens extract powder is widely used in clinical practice for the treatment of tumors, M2-b type leukemia, and acute and chronic tonsillitis and pharyngitis, and is known as "the penicillin of traditional Chinese medicine".
Rabdosia Rubescens Extract Raw Material Advantages
1.High-quality raw materials for Rabdosia rubescens
We select Rabdosia rubescens from the golden production area of Jiyuan, Henan Province as raw materials. The content of Rabdosia rubescens A and B in the Rabdosia rubescens produced in this area is significantly higher than that in other production areas.
The unique local climate and soil conditions, along with the inherent cold-resistant, drought-resistant, and barren-tolerant characteristics of Rhizoma Isodon, allow the raw materials to grow naturally without human intervention, thus possessing a high level of active ingredients. Through a fully controlled supply chain system, we ensure that every batch of raw materials meets stable and efficient quality standards.
2.Strict Quality Control System
Rabdosia Rubescens we select grows in pristine natural environments such as mountains and forest edges at altitudes of 100-2800 meters. In addition, we have established a full-process quality control standard from planting to extraction to ensure that Rhizoma Rabdosia A and B maintain high bioavailability, providing customers with raw materials that are closer to the efficacy of natural medicine. You can rest assured to use our Rhizoma Rabdosia extract powder to develop your pharmaceutical products.
Rabdosia Rubescens we select grows in pristine natural environments such as mountains and forest edges at altitudes of 100-2800 meters. In addition, we have established a full-process quality control standard from planting to extraction to ensure that Rhizoma Rabdosia A and B maintain high bioavailability, providing customers with raw materials that are closer to the efficacy of natural medicine. You can rest assured to use our Rhizoma Rabdosia extract powder to develop your pharmaceutical products.
3.Stable and Sustainable Supply
Taking advantage of the storage-resistant and vigorous sprouting characteristics of rabdosia rubescens, we have established a large-scale raw material reserve, which can meet customers' long-term, large-volume procurement needs without worrying about supply interruptions. We consistently provide more competitive prices while ensuring high levels of phytoestrogens A and B, helping customers reduce production costs and increase the added value of their end products.
Rabdosia Rubescens Extract Oridonin Specification
| Item | Specifications | Results |
|---|---|---|
| Appearance | White powder | Conforms |
| Assay | ≥98.0% | 99.15% |
| Odor | Characteristic | Conforms |
| Loss on Drying | ≤5.0% | 1.72% |
| Mesh Size | 100% pass 80 mesh | Conforms |
| Residue analysis | ||
| As | ≤1.0 ppm | Conforms |
| Pb | ≤1.0 ppm | Conforms |
| Hg | ≤0.1ppm | Conforms |
| Cd | ≤1.0 ppm | Conforms |
| Solvents Residue | ≤1000 ppm | Conforms |
| Microbiological Tests | ||
| Total plate count(cfu/g) | ≤1000 cfu/g | Conforms |
| Yeast & Mold count(cfu/g) | ≤100 cfu/g | Conforms |
| E.coli | Negative | Conforms |
| Salmonella | Negative | Conforms |
| Staphylococcus | Negative | Conforms |
| Conclusion | Confirm to Specification and Standards. | |
Rabdosia Rubescens Extract Oridonin Powder Production Process
Rabdosia Rubescens Extract Benefits
Rabdosia rubescens extract benefits for anti-cancer
Oridonin, a natural diterpenoid compound, has a good inhibitory effect on the proliferation of various cancer cells. It induces cancer cell apoptosis, inhibits cancer cell proliferation and metastasis, arrests the cell cycle, and prevents tumor invasion, metastasis, and angiogenesis by regulating multiple cell signaling pathways (such as PI3K/AKT, MAPK, etc.).
It can also regulate the tumor immune microenvironment and enhance the anti-tumor activity of immune cells. In addition, oridonin can produce significant synergistic effects with chemotherapy drugs and targeted therapies, effectively reducing drug resistance in cancer cells and providing an important direction for optimizing tumor treatment plans.
Our rubescensin A raw material has stable quality and controllable activity, and can be used as a core raw material for the research and development of various anti-tumor related drugs.
Our rubescensin A raw material has stable quality and controllable activity, and can be used as a core raw material for the research and development of various anti-tumor related drugs.
Reference: https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2025.1606325/full; https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsn3.3986.
Rabdosia rubescens extract benefits for antibacterial
Rabdosia rubescens extract has good broad-spectrum antibacterial activity and can effectively inhibit Gram-positive bacteria such as Staphylococcus aureus and fungi. It mainly works by disrupting bacterial cell membranes and interfering with bacterial metabolism. It can also synergistically enhance the antifungal effect with existing antibiotics (such as azole drugs), providing a potential natural source candidate compound for the development of novel antibacterial drugs.
In addition, Kintainutri® contains oridonin A, extracted from natural Rhizoma Rabdosiae, which has high safety and potential applications in food preservation and antibacterial product development.
Rabdosia rubescens extract benefits for Anti-inflammatory and analgesic
As a traditional Chinese medicine, Isodon rubescens extract has the effects of clearing heat and detoxifying, promoting blood circulation and relieving pain. Traditionally, it can effectively relieve pain and inflammatory reactions caused by sore throat, sores and snake bites.
Modern research has confirmed that its core active ingredient, oridonin, can effectively reduce the level of pro-inflammatory factors and alleviate tissue damage by inhibiting inflammatory signaling pathways and regulating the function of immune cells, thereby exerting anti-inflammatory and analgesic effects and improving various inflammatory-related diseases.
Image by https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1512740/full.
Reference: https://www.dovepress.com/article/download/109267; https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2025.1585057/full.
Rabdosia rubescens extract benefits for antiviral
Studies have shown that the main active ingredient of Rabdosia rubescens, oridonin, can effectively inhibit the replication of herpes simplex virus type 1, and also shows significant inhibitory effects on SARS-CoV-2 and its Omeprone variant, as well as bat coronaviruses.
Its mechanism of action primarily involves targeting the virus's main protease (Mpro) and covalently binding to it, thereby blocking the hydrolysis of viral precursor proteins and inhibiting the replication and proliferation of viral genetic material. Therefore, you can use our oridonin to develop novel antiviral drugs.
What is rabdosia rubescens extract used for?
Rabdosia rubescens extract supplement
Currently, marketed supplements containing rabdosia rubescens extract mainly include syrups, lozenges, and pills. Approved products include oridonin tablets, capsules, pills, and lozenges. These can be used to treat acute pharyngitis, chronic tonsillitis, and oral ulcers.
Where can I buy rabdosia rubescens extract online?
Kintainutri® has over 10 years of experience in the plant extract industry, possessing a mature R&D and production system and strict quality control capabilities. We supply a variety of specifications of Oridonin extract, including 0.5%, 1%, 5%, and 98% concentrations of Oridonin and 98% concentration of Ponicidin, to meet different usage needs.
By relying on standardized production processes and professional HPLC testing standards, we can precisely control the purity and activity of our products, enabling us to provide customers with stable and high-quality extracts. *Kintainutri® Promise All Products: Non-Irradiated / Non-ETO/ Treat by Heat Only / Non-GMO
Shipping & Packaging
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● Packaging: Inside food grade bag, outer aluminum foil bag.25kg use double-layer plastic container/fiber drum.Or your choice.● OEM Service Available: Customized packaging available, click here to know more.● Shipping: DHL / FEDEX / EMS/ BY AIR / BY SEA● American Warehouse: KINTAI put over 100 natural plant extract ingredients in our US warehouse for fast delivery.● Payment: We accept payment by T/T, L/C, Paypal, and Wester Union.Please contact us and we will guide you with an easy and professional way for your order.
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